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A team consisting of Bruce Appel, Professor and Head of the Section of Developmental Biology and Diane G. Wallach Chair of Pediatric Stem Cell Biology, Wendy Macklin, Professor and Chair of the Department of Cell and Developmental Biology, Santos Franco, Associate Professor of Developmental Biology, and Ethan Hughes, Associate Professor of Cell and Developmental Biology, received one of three 2025 CU ASPIRE awards. Their project, entitled, “Molecular Mechanisms of Activity-Regulated Myelination” aims to determine how neuronal activity regulates gene expression in myelinating glial cells.
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We recieved a new NIMH R21 grant entitled, “A Synaptogenic Adhesion Code for Myelin Specificity”. This project aims to elucidate underlying causes of white matter abnormalities in neurodevelopmental disorders. This is our first grant from NIMH!
Sheila Gupta, a MSTP and Molecular Biology student, received a three year NRSA F31 fellowship award from the National Institute of Neurological Disorders and Stroke for her project entitled, “Axon selection for myelination by excitatory postsynaptic factors”.
Katie Ranard received an NIH/NINDS K99/R00 Pathway to Independence Award (K99NS144387) to study how nutritional status impacts mechanisms guiding brain development. Her project will use a novel omega-3 fatty acid deficient zebrafish model and powerful live-imaging approaches to reveal the role of maternal nutrition in neurodevelopment at single-cell resolution.
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