OUR MISSION
Research
We aim to discover genetic, molecular, and cellular mechanisms that guide development of the central nervous system and use this information to understand causes of childhood neurological disorders. We use a variety of experimental approaches including single cell RNA-sequencing to identify gene regulatory networks that coordinate cell fate and differentiation, genome modification and transgenesis to test gene functions, pharmacological and chemogenetic methods to manipulate neural activity, and confocal light imaging of cell behaviors in living zebrafish embryos and larvae.
We aim to discover genetic, molecular, and cellular mechanisms that guide development of the central nervous system and use this information to understand causes of childhood neurological disorders. We use a variety of experimental approaches including single cell RNA-sequencing to identify gene regulatory networks that coordinate cell fate and differentiation, genome modification and transgenesis to test gene functions, pharmacological and chemogenetic methods to manipulate neural activity, and confocal light imaging of cell behaviors in living zebrafish embryos and larvae.
Education and Training
Our lab members include graduate students, postdoctoral fellows, high school and undergraduate research interns, medical trainees, and research staff. Lab members have their own independent but related research projects, creating a rich environment for sharing different perspectives, knowledge, and expertise. We strive to become independent, creative, confident, motivated, rigorous, and generous researchers and scholars with excellent communication and professional skills.
Our lab members include graduate students, postdoctoral fellows, high school and undergraduate research interns, medical trainees, and research staff. Lab members have their own independent but related research projects, creating a rich environment for sharing different perspectives, knowledge, and expertise. We strive to become independent, creative, confident, motivated, rigorous, and generous researchers and scholars with excellent communication and professional skills.
OUR COMMUNITY
We are members of the Department of Pediatrics, Section of Developmental Biology, the only Section in Pediatrics exclusively committed to basic and translational research and training. Additionally, we have a close relationship with Children's Hospital Colorado. Graduate students in our lab are drawn from three training programs: Cell Biology, Stems Cells and Development (CSD), Neuroscience (NSP), and Molecular Biology (Mol Bio). The exceptionally collegial and supportive nature of researchers and trainees on our campus creates a rich intellectual environment and provides numerous opportunities for collaborative, interdisciplinary research.
University of Colorado Anschutz Medical Campus
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image credits - Yuying Wang, Alex Hughes, Caleb Doll, Andy Ravanelli, Oscar Mendez, Hae-Chul Park, Natalie Carey
