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We have been generously funded, primarily by the NIH, since 1999. Currently, most of our funding is from NINDS in the form of a large R35 award, a collaborative R01 grant shared with the Franco and Sagerstrom labs, and four NRSA training fellowships. We also have benefited by excellent support from the Gates Frontiers Fund and the Diane G. Wallach Chair in Pediatric Stem Cell Biology. Our current support is detailed below.
NINDS R35NS122191 "Mechanisms of Developmental Myelination" (Appel, PI) 05/2021 – 04/2029
NIMH R21MH140123 "A Synaptogenic Adhesion Code for Myelin Specificity" (Appel, PI) 04/21/2025 - 03/31/2027
NINDS R01NS124166 "Temporal and Spatial Control of Oligodendrocyte Fate Specification" (Franco, Sagerström, Appel, MPI) 07/01/2022 – 05/31/2027
NIDDK R01DK064380 "Molecular Mechanisms of Polarized Endocytic Traffic in Epithelial Cells" (Prekeris, PI; Appel, Co-I) 1/15/2004 – 6/30/2024
NIMH 1K99NS144387 "Impact of Nutrional Status on Mechanisms Guiding Brain Development (Ranard, PI) 08/01/2025 - 07/30/2027
NINDS F31NS145735 "Axon Section for Myelination by Excitatory Postsynaptic Factors) (Gupta, PI) 08/01/2025 - 07/30/2028
NINDS F31NS125915 "Oligodendrocyte Lineage Cell Mechanisms of Axon Selection for Myelination" (Carey, PI) 05/05/2022-04/30/2025
NINDS F32NS131216 "Examining the regulation of resident mRNAs in myelin plasticity" (Adula, PI) 04/01/2023 - 03/31/2026
NINDS F32NS131175 "Role of n-3 polyunsaturated fatty acids in myelination during development" (Renard, PI) 04/01/2023 - 03/31/2025
NINDS F32NS134612 "Investigating the role of Wnt signaling effectors on the neuron-glia switch and OPC specification during development and after injury" (Arena, PI) 01/01/2024 - 12/31/2026
NIGMS T32GM14172 "Predoctoral Training in Genetics of Development, Disease, and Regeneration" (Appel, Co-PI and Director) 01/2021 – 06/2028
Colorado Clinical and Translational Sciences Institute and HDSA Center of Excellence at the University of Colorado Movement Disorders Center Pilot Grant Award, "Unraveling neurodevelopmental mechanisms of mutant Huntington protein in non-neuronal cell types" (Appel, PI; Souder, Co-PI) 04/01/2023 - 03/31/2024
Glendorn Foundation,"Unraveling neurodevelopmental mechanisms of mutant Huntington protein in non-neuronal cell types" (Appel, PI; Souder, Co-PI) 12/01/2023 - 11/30/2024
Diane G. Wallach Chair of Pediatric Stem Cell Biology
NINDS R35NS122191 "Mechanisms of Developmental Myelination" (Appel, PI) 05/2021 – 04/2029
NIMH R21MH140123 "A Synaptogenic Adhesion Code for Myelin Specificity" (Appel, PI) 04/21/2025 - 03/31/2027
NINDS R01NS124166 "Temporal and Spatial Control of Oligodendrocyte Fate Specification" (Franco, Sagerström, Appel, MPI) 07/01/2022 – 05/31/2027
NIDDK R01DK064380 "Molecular Mechanisms of Polarized Endocytic Traffic in Epithelial Cells" (Prekeris, PI; Appel, Co-I) 1/15/2004 – 6/30/2024
NIMH 1K99NS144387 "Impact of Nutrional Status on Mechanisms Guiding Brain Development (Ranard, PI) 08/01/2025 - 07/30/2027
NINDS F31NS145735 "Axon Section for Myelination by Excitatory Postsynaptic Factors) (Gupta, PI) 08/01/2025 - 07/30/2028
NINDS F31NS125915 "Oligodendrocyte Lineage Cell Mechanisms of Axon Selection for Myelination" (Carey, PI) 05/05/2022-04/30/2025
NINDS F32NS131216 "Examining the regulation of resident mRNAs in myelin plasticity" (Adula, PI) 04/01/2023 - 03/31/2026
NINDS F32NS131175 "Role of n-3 polyunsaturated fatty acids in myelination during development" (Renard, PI) 04/01/2023 - 03/31/2025
NINDS F32NS134612 "Investigating the role of Wnt signaling effectors on the neuron-glia switch and OPC specification during development and after injury" (Arena, PI) 01/01/2024 - 12/31/2026
NIGMS T32GM14172 "Predoctoral Training in Genetics of Development, Disease, and Regeneration" (Appel, Co-PI and Director) 01/2021 – 06/2028
Colorado Clinical and Translational Sciences Institute and HDSA Center of Excellence at the University of Colorado Movement Disorders Center Pilot Grant Award, "Unraveling neurodevelopmental mechanisms of mutant Huntington protein in non-neuronal cell types" (Appel, PI; Souder, Co-PI) 04/01/2023 - 03/31/2024
Glendorn Foundation,"Unraveling neurodevelopmental mechanisms of mutant Huntington protein in non-neuronal cell types" (Appel, PI; Souder, Co-PI) 12/01/2023 - 11/30/2024
Diane G. Wallach Chair of Pediatric Stem Cell Biology